Association of a Polymorphism of the Transforming Growth Factor-β1 Gene with Genetic Susceptibility to Osteoporosis in Postmenopausal Japanese Women
Open Access
- 1 October 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Bone and Mineral Research
- Vol. 13 (10) , 1569-1576
- https://doi.org/10.1359/jbmr.1998.13.10.1569
Abstract
Transforming growth factor-β (TGF-β) is both abundant in bone and an important regulator of bone metabolism. A T→C transition at nucleotide 29 in the signal sequence region of the TGF-β1 gene results...Keywords
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