A computer case definition for sudden cardiac death
- 22 December 2009
- journal article
- research article
- Published by Wiley in Pharmacoepidemiology and Drug Safety
- Vol. 19 (6) , 563-572
- https://doi.org/10.1002/pds.1888
Abstract
Purpose: To facilitate studies of medications and sudden cardiac death, we developed and validated a computer case definition for these deaths. The study of community dwelling Tennessee Medicaid enrollees 30–74 years of age utilized a linked database with Medicaid inpatient/outpatient files, state death certificate files, and a state ‘all‐payers’ hospital discharge file.Methods: The computerized case definition was developed from a retrospective cohort study of sudden cardiac deaths occurring between 1990 and 1993. Medical records for 926 potential cases had been adjudicated for this study to determine if they met the clinical definition for sudden cardiac death occurring in the community and were likely to be due to ventricular tachyarrhythmias. The computerized case definition included deaths with (1) no evidence of a terminal hospital admission/nursing home stay in any of the data sources; (2) an underlying cause of death code consistent with sudden cardiac death; and (3) no terminal procedures inconsistent with unresuscitated cardiac arrest. This definition was validated in an independent sample of 174 adjudicated deaths occurring between 1994 and 2005.Results: The positive predictive value of the computer case definition was 86.0% in the development sample and 86.8% in the validation sample. The positive predictive value did not vary materially for deaths coded according to the ICO‐9 (1994–1998, positive predictive value = 85.1%) or ICD‐10 (1999–2005, 87.4%) systems.Conclusion: A computerized Medicaid database, linked with death certificate files and a state hospital discharge database, can be used for a computer case definition of sudden cardiac death. Copyright © 2009 John Wiley & Sons, Ltd.Keywords
This publication has 31 references indexed in Scilit:
- Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac DeathNew England Journal of Medicine, 2009
- Validation of ICD‐9 codes with a high positive predictive value for incident strokes resulting in hospitalization using Medicaid health dataPharmacoepidemiology and Drug Safety, 2007
- A comparison of death certificate out-of-hospital coronary heart disease death with physician-adjudicated sudden cardiac deathThe American Journal of Cardiology, 2005
- Drug-Induced Prolongation of the QT IntervalNew England Journal of Medicine, 2004
- QT Prolongation with Antimicrobial AgentsDrugs, 2004
- Validation of Death Certificate Diagnosis of Out-of-Hospital Coronary Heart Disease Deaths in Olmsted County, MinnesotaMayo Clinic Proceedings, 2000
- Validation of death certificate diagnosis of out-of-hospital sudden cardiac deathThe American Journal of Cardiology, 1998
- Use and accuracy of state death certificates for classification of sudden cardiac deaths in high-risk populationsAmerican Heart Journal, 1997
- Mechanism of death and prevalence of myocardial ischemic symptoms in the terminal event after acute myocardial infarctionThe American Journal of Cardiology, 1988
- Clinical classification of cardiac deaths.Circulation, 1982