Evidence that the immediate biosynthetic precursor of clavulanic acid is its N-aldehyde analogue
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 11,p. 1281-1282
- https://doi.org/10.1039/c39940001281
Abstract
(3R, 5R) Clavulanate-9-aldehyde 1 has been detected in Streptomyces clavuligerus and an NADPH dependent dehydrogenase capable of reducing 1 to clavulanic acid 2 has been isolated from this organism.Keywords
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