THE SCREENING OF PATIENTS WITH SUSPECTED THYROTOXICOSIS USING A SENSITIVE TSH RADIOIMMUNOASSAY
- 1 April 1985
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 22 (4) , 445-451
- https://doi.org/10.1111/j.1365-2265.1985.tb00143.x
Abstract
A radioimmunoassay was optimized to measure serum TSH with maximum sensitivity (sTSH). With this assay sTSH was < 0.5 mIU/l in 100% of 64 patients with proven thyrotoxicosis and > 0.5 mIU/l in 92% of 76 normal subjects. sTSH correctly predicted the TSH response to TRH (.DELTA. TSH) in 93% of 125 patients with suspected thyrotoxicosis. In this group thyrotoxicosis was excluded by an sTSH > 0.5 mIU/l in 52% of patients thus avoiding the need for further testing.This publication has 10 references indexed in Scilit:
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