Mapping of the linkage group GLO-Bf-HLA-B,C,A-PGM3
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 44 (3) , 313-319
- https://doi.org/10.1007/bf00394296
Abstract
This study confirms close linkage for the GLO-Bf-HLA-B,C,A complex, and proves linkage between the MHC loci and PGM3. For GLO-PGM3 and Bf-PGM3, respectively, loose linkage seems to be likely, and close linkage can be excluded. Our mapping data on chromosomle 6 favor the hypothesis that the PGM3 locus is situated on the HLA-A side of the MHC complex. Yet fine-structure mapping should be confirmed only by segregation analyses in crossover families by testing simultaneously all of the relevant marker loci within uniform family material.Keywords
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