Mycoplasma pneumoniae infection complicated by paroxysmal cold hemoglobinuria with anti-P specificity of biphasic hemolysin
- 1 March 1977
- journal article
- research article
- Published by Springer Nature in Annals of Hematology
- Vol. 34 (3) , 211-214
- https://doi.org/10.1007/bf00996170
Abstract
A 7-year-old boy with Mycoplasma Pneumoniae infection complicated by transitory paroxysmal cold haemoglobinuria (PCH) is described. The Donath-Landsteinerantibody exhibited anti-P specificity; hemolytic activity was partially inhibited against papainized erythrocytes at 0° C incubation temperature and increased from 8° C upwards. The association of Mycoplasma pneumoniae infection with PCH has been described 4 times only and in one instance where specificity was stated it was anti-I. Bei einem 7jährigen Jungen trat im Anschluß an eine Pneumonie durch Mykoplasma pneumoniae eine akute passagere Kältehämoglobinurie auf. Der Donath-LandsteinerAntikörper zeigte Anti-P-Spezifität. Die hämolytische Aktivität gegen papainisierte Erythrozyten wurde bei einer Inkubationstemperatur von 0° C teilweise gehemmt und stieg bei Inkubationstemperaturen von über 8° C an. Das Auftreten einer passageren Kältehämoglobinurie im Anschluß an eine Infektion mit M. pneumoniae wurde bisher nur viermal beschrieben; nur in einem Fall wurde die Spezifität angegeben, dabei handelte es sich um Anti-I.Keywords
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