Peptides. Part XXIX. Synthesis of canine gastrin and a new synthesis of human gastrin
- 1 January 1969
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- Vol. 16 (17) , 2213-2217
- https://doi.org/10.1039/j39690002213
Abstract
The heptadecapeptide amide [graphic omitted]lu-Gly-Pro-Trp-Met-Glu-Glu-Ala-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2(canine gastrin I) has been synthesised by a new general route, and the [Leu5,Glu8]-analogue (human gastrin I) by a variant of it. O-Acylation of tyrosine derivatives by N-hydroxysuccinimide esters was found to occur in aqueous but not in anhydrous solution.Keywords
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