Meprobamate Overdosage
- 1 March 1985
- journal article
- case report
- Published by SAGE Publications in Human Toxicology
- Vol. 4 (2) , 215-217
- https://doi.org/10.1177/096032718500400212
Abstract
Meprobamate is a non-barbiturate hypnotic/tranquillizer, first used clinically in 1955. One preparation (Tenavoid; Edwin Burgess) contains meprobamate and bendrofluazide and is prescribed for pre-menstrual tension. In adults therapeutic plasma meprobamate concentrations range up to 10 mg/l and unwanted side-effects occur at greater than 40 mg/l. Light coma occurs at 60-120 mg/l and deep coma at 100-240 mg/l (Baselt, 1982). There are no data on toxic plasma concentrations in children. We report two cases of overdosage in children who regained consciousness at times when plasma meprobamate concentrations were greater than 100 mg/l.Keywords
This publication has 1 reference indexed in Scilit:
- Poisoning Diagnosis and TreatmentPublished by Springer Nature ,1981