Effect of Fresh Plasma Infusions on the Sensitized Sheep Cell Agglutination Reaction in Cases of Rheumatoid Disease

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Abstract
Five patients with rheumatoid disease with high Rose-Waaler titers were given multiple infusions of fresh plasma. This procedure was followed by a significant fall in the titer to normal or near normal levels. The effect was transient. Coincidentally the erythrocyte sedimentation rate declined with the reversion of the Rose-Waaler titer to normal. This also was a transient phenomenon. The therapeutic value of fresh plasma as a form of treatment in rheumatoid disease was not assessed.