Childhood Sarcoidosis — A Study of 18 Patients

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Abstract
Of 18 children with a tissue diagnosis of sarcoidosis 11 were symptomatic; seven were asymptomatic, but on routine x-ray study exhibited hilar adenopathy often combined with pulmonary mottling. The children with symptoms were younger, had more extensive disease and a longer and more complicated course of illness than those who were asymptomatic; they frequently required glucocorticosteroids or chloroquine. The asymptomatic children fared better than those with symptoms. Asymptomatic sarcoidosis in children is more frequent than is currently recognized but its true prevalence is likely to remain unknown, since mass chest x-ray surveys and routine chest radiography are not systematically pursued in tuberculin-negative children. Earlier recognition of sarcoidosis in children may prevent some of the complications of this disorder such as blindness and pulmonary insufficiency.

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