Unbinding of lipid bilayers induced by osmotic pressure in relation to unilamellar vesicle formation
- 10 October 2007
- journal article
- Published by IOP Publishing in Europhysics Letters
- Vol. 80 (4) , 48002
- https://doi.org/10.1209/0295-5075/80/48002
Abstract
Small-angle X-ray scattering and phase-contrast microscopy experiments were performed to investigate the effect of osmotic pressure on vesicle formation in a dioleoylphosphatidylcholine (DOPC)/water/NaI system. The multi-lamellar structure of lipid bilayers is unstabilized when a lipid film with a sufficient amount of NaI is hydrated by pure water. It has been confirmed that this phenomenon is due to the effect of osmotic pressure induced by a heterogeneous distribution of NaI molecules. This could be the origin of the unbinding of lipid bilayers to conform large uni-lamellar vesicles.Keywords
All Related Versions
This publication has 23 references indexed in Scilit:
- Diffuse scattering provides material parameters and electron density profiles of biomembranesPhysical Review E, 2004
- Discontinuous Unbinding of Lipid MultibilayersPhysical Review Letters, 2003
- Preparation of cell-size unilamellar liposomes with high captured volume and defined size distributionPublished by Elsevier ,2003
- Salt-induced phase separation in the liquid crystalline phase of phosphatidylcholinesColloids and Surfaces A: Physicochemical and Engineering Aspects, 2001
- Thermal Unbinding of Highly Oriented Phospholipid MembranesPhysical Review Letters, 2000
- Spontaneous Formation of Giant Liposomes from Neutral PhospholipidsChemistry Letters, 1997
- Small-angle neutron scattering from multilamellar lipid bilayers: Theory, model, and experimentPhysical Review E, 1996
- Experimental Study of Undulation Forces in a Nonionic Lamellar PhaseLangmuir, 1996
- Flory theory of the unbinding transitionJournal de Physique I, 1992
- Unbinding Transitions of Interacting MembranesPhysical Review Letters, 1986