Tetranactin, a New Miticidal Antibiotic. III. Miticidal and Other Biological Properties1

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Abstract
In screening for pesticidal antibiotics with Callosobruchus chinensis L. as a test insect, we isolated a new crystal-line antibiotic, tetranactin, from Streptomyces aureus Waksman and Henrici. Tetranactin shows remarkable miticidal activity and low toxicity to warm-blooded animals. Miticidal activity is significant against the carmine spider mite, Tetranychus cinnabarinus (Boisduval); the two spotted Koch, the European red mite, Panonychus ulmi (Koch); Tetranychus kanzawa (Kishida); and T. viennensis (Zacher) by spray tests in a green house. Adults of these mites are more sensitive than the eggs. Proliferation of T. kanzawa and the European red mite also was suppressed by a spray of the antibiotic in a field test. Tetranactin is a selective miticidal agent since the antibiotic is relatively nontoxic to an insect. Thus, the antibiotic is the 1st potential miticidal antibiotic in view of its strong and selective activity and low toxicity.

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