Betaxolol and Restrictive Airway Disease

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Abstract
To the Editor. —Betaxolo hydrochloride, a β1 adrenergic receptor blocking agent, has a low incidence of systemic effects and has been shown to be clinically safe and effective for the treatment of glaucoma.1 However, a recent case report has documented respiratory problems with the use of topical betaxolo.2 We wish to report a case of reduction in pulmonary capacity following the use of topical betaxolol, as well as the failure of systemic therapy to alleviate symptoms, in a patient with minimal reactive airway disease. Report of a Case. —A 71-year-old woman had pseudoexfoliative glaucoma of the right eye. Ocular tensions in this eye ranged from 25 to 30 mm Hg. The optic disc had a cup-to-disc ratio of 0.9. A superior paracentral scotoma was present in the right eye. The left eye had a normal intraocular pressure, cup-to-disc ratio, and visual field. She was allergic to pilocarpine

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