Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts
Top Cited Papers
- 30 September 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 125 (42) , 12672-12673
- https://doi.org/10.1021/ja036972z
Abstract
Michael reaction of malonates to nitroolefins with chiral bifunctional organocatalysts, bearing both a thiourea and tertiary amino group, afforded Michael adducts with high yields and enantioselectivities (up to 95%, up to 93% ee).Keywords
This publication has 22 references indexed in Scilit:
- Thiourea-catalyzed nucleophilic addition of TMSCN and ketene silyl acetals to nitrones and aldehydesTetrahedron Letters, 2003
- Metal‐Free, Noncovalent Catalysis of Diels–Alder Reactions byNeutralHydrogen Bond Donors in Organic Solvents and in WaterChemistry – A European Journal, 2003
- First Synthesis of a β2-Homoamino Acid by Enantioselective CatalysisOrganic Letters, 2002
- Asymmetric Catalytic Mannich Reactions Catalyzed by Urea Derivatives: Enantioselective Synthesis of β-Aryl-β-Amino AcidsJournal of the American Chemical Society, 2002
- Asymmetric Alkylation of tert-Butyl Glycinate Schiff Base with Chiral Quaternary Ammonium Salt under Micellar ConditionsOrganic Letters, 2001
- (S)-3,3‘-Dimethyl-2,2‘-biquinoline N,N‘-Dioxide as an Efficient Catalyst for Enantioselective Addition of Allyltrichlorosilanes to AldehydesJournal of the American Chemical Society, 1998
- Hydrogen bond-directed cocrystallization and molecular recognition properties of diarylureasJournal of the American Chemical Society, 1990
- The stereoselective synthesis of .alpha.-amino acids by phase-transfer catalysisJournal of the American Chemical Society, 1989
- Efficient catalytic asymmetric alkylations. 1. Enantioselective synthesis of (+)-indacrinone via chiral phase-transfer catalysisJournal of the American Chemical Society, 1984
- Asymmetric addition of thioglycolic acid to nitro olefins catalyzed by cinchona alkaloidsThe Journal of Organic Chemistry, 1981