Multiple Biopsies in Head and Neck Cancer
- 1 August 1969
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 90 (2) , 159-163
- https://doi.org/10.1001/archotol.1969.00770030161013
Abstract
THE MULTIPLICITY of malignant primary tumors of the upper respiratory and digestive tracts was recognized as early as 1879 by Billroth1 and since then there have been numerous articles concerned with this problem. The tumors may be obvious and easily recognized or not so obvious and microscopic in size and easily missed even by the careful and trained examiner. In some instances new primary cancers develop years after the discovery of the first primary tumor. It is imperative for the physician entrusted with the treatment of a patient with cancer of the larynx, pharynx and oral cavity, and esophagus to be alert to the possibility of the existence of another primary malignant tumor. Obviously, the sooner such new primaries are detected, the more effective and rewarding the treatment will be. In view of the frequency of multiple primary cancers in the head and neck area, it has been theKeywords
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