Dominant expression of the T cell receptor BALB invariant δ (BID) chain in resident pulmonary lymphocytes is due to selection
- 1 March 1991
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 21 (3) , 859-861
- https://doi.org/10.1002/eji.1830210352
Abstract
During ontogeny, the T cell receptor BALB invariant δ (BID) chain (Sim, G.-K. and Augustin, A., Cell 1990. 61: 397) is generated in C57BL/6 fetal thymocytes at levels similar to those detected in BALB/c mice. Hence, the dominance of BID observed among resident pulmonary lymphocytes of BALB/c and of (BALB/c x C57BL/6) F1 and its absence in C57BL/6 mice is due to positive selection and peripheral expansion rather than to the inability of C57BL/6 mice to generate this particular rearrangement.Keywords
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