Cardiovascular Effects of Vasopressin Infused into the Vertebral Circulation of Conscious Dogs

Publisher Website
Google Scholar
Abstract
Seven conscious dogs received arginine-vasopressin infusions (100 and 1000 f[femto]mol min-1 per kg) through catheters implanted in the left vertebral artery or the inferior vena cava while arterial pressure, cardiac output (electromagnetic flowmeter) and heart rate were measured. Despite similar increases in plasma vasopressin concentrations, intravertebral administration induced a lesser increase in mean arterial pressure and a greater decrease in heart rate than the same infusion given i.v. Vasopressin apparently has an effect on structures of the CNS involved in cardiovascular control, possibly by affecting the baroreceptor reflex.

This publication has 1 reference indexed in Scilit: