Syntheses of all singly labeled [ 15 N]adenines: Mass spectral fragmentation of adenine

Abstract
Syntheses of all five of the singly labeled [ 15 N]adenines are now provided. The presence or absence of two-bond 15 N- 1 H spin couplings in their 1 H NMR spectra confirm the location of the isotope in each case. The fragmentation patterns in their mass spectra are indicative of the sequential losses of HCN units and of CH 2 N 2 from adenine upon electron impact.

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