POLYARTHRITIS ASSOCIATED WITH HEPATITIS C VIRUS INFECTION
- 1 March 1994
- journal article
- case report
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 33 (3) , 289-291
- https://doi.org/10.1093/rheumatology/33.3.289
Abstract
Two cases of polyarthritis associated with hepatitis C infection are reported. In Patient 1, stiffness and polyarthritis occurred during the acute stage of hepatitis. The arthritic symptoms lasted for 4 months. A transient polyarthritis recurred 4 yr later. The persistent presence of anti-hepatitis C viral antibodies was noted. Hepatitis C viral RNA (HCV RNA) was identified in the serum using the polymerase chain reaction proving that the patient was a carrier. In Patient 2, polyarthritis occurred associated with chronic hepatitis C liver disease. Synovial iopsy showed infiltration of mononuclear cells HCV RNA was demonstrated in both serum and SF. These cases suggest an aetiologic association between arthritis and hepatitis C antigenaemia.Keywords
This publication has 0 references indexed in Scilit: