Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

This publication has 40 references indexed in Scilit:

• Purification and Characterization of a Z-Leu-Leu-Leu-MCA Degrading Protease Expected to Regulate Neurite Formation: A Novel Catalytic Activity in Proteasome
  Biochemical and Biophysical Research Communications, 1993
• A role for the ubiquitin-dependent proteolytic pathway in MHC class l-restricted antigen presentation
  Nature, 1993
• The Biochemistry and Cell Biology of Antigen Processing and Presentation
  Annual Review of Immunology, 1993
• A molecular model of MHC class-I-restricted antigen processing
  Immunology Today, 1992
• Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules
  Nature, 1992
• THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION
  Annual Review of Biochemistry, 1992
• Improved method for preparation of ubiquitin‐ligated lysozyme as substrate of ATP‐dependent proteolysis
  FEBS Letters, 1991
• ATP‐dependent reversible association of proteasomes with multiple protein components to form 26S complexes that degrade ubiquitinated proteins in human HL‐60 cells
  FEBS Letters, 1991
• The conformational flexibility of class I H-2 molecules as revealed by anti-peptide antibodies specific for intracytoplasmic determinants: Differential reactivity of β2-microglobulin “bound” and “free” H-2Kb heavy chains
  Molecular Immunology, 1990
• Introduction of soluble protein into the class I pathway of antigen processing and presentation
  Cell, 1988