Increased Growth after Long-Term Oral 1α,25-Vitamin D3in Childhood Renal Osteodystrophy
- 2 February 1978
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 298 (5) , 238-242
- https://doi.org/10.1056/nejm197802022980503
Abstract
We evaluated oral 1,25-vitamin D3 for as long as 26 months in six prepubescent children with renal osteodystrophy previously treated with vitamin D2. Therapy was given at 14 to 41 ng per kilogram per day to correct hypocalcemia and reverse bone disease. Serum levels of 1,25-vitamin D3 were initially reduced at 15±5 pg per milliliter (mean ± S.E.M.) and after treatment rose to 54±13. Serum calcium rose from 7.5±1.6 mg per deciliter (mean ± S.D.) to 9.8±0.6 after one month (P3 can reverse renal bone disease and increase growth in uremic children. (N Engl J Med 298:238–242, 1978)This publication has 25 references indexed in Scilit:
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