Isolation, Structure, and Synthesis of a Human Seminal Plasma Peptide with Inhibin-Like Activity
- 16 March 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 223 (4641) , 1199-1202
- https://doi.org/10.1126/science.6422553
Abstract
A basic peptide isolated from pooled human seminal plasma exhibited inhibin-like activity by suppressing pituitary follicle-stimulating hormone secretion in vitro and in vivo. The peptide has been characterized and sequenced, and a 31-amino-acid synthetic replicate showed full biological activity in vitro.This publication has 16 references indexed in Scilit:
- Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factorNature, 1983
- Isolation, analysis of structure, synthesis, and biological actions of urotensin I neuropeptidesCanadian Journal of Biochemistry and Cell Biology, 1983
- ISOLATION AND CHARACTERIZATION OF INHIBIN FROM HUMAN SEMINAL PLASMA*Annals of the New York Academy of Sciences, 1982
- Inhibin is absent from azoospermic semen of infertile menNature, 1980
- Inhibin — fact or artifactMolecular and Cellular Endocrinology, 1979
- Aspects of Hypothalamic Regulation of the Pituitary GlandScience, 1978
- Total synthesis of ovine-.beta.-lipotropin by the solid-phase methodJournal of the American Chemical Society, 1978
- Evidence for inhibin-like activity in bovine follicular fluidNature, 1976
- Solid Phase Peptide Synthesis. I. The Synthesis of a TetrapeptideJournal of the American Chemical Society, 1963
- Dual Endocrine Activity of the TestesScience, 1932