Dissecting the Epidermal Growth Factor Receptor Signal Transactivation Pathway

1 January 2006

book chapter
Published by Springer Nature

Vol. 327, 85-98
https://doi.org/10.1385/1-59745-012-x:85

Abstract

Interreceptor cross-talk has emerged as a general concept in cellular signaling cascades. Therein epidermal growth factor receptor (EGFR) signal transactivation represents the so far best...

Keywords

EGFR
HEPARIN-BINDING EPIDERMAL GROWTH FACTOR (HB-EGF)
EGF-LIKE LIGAND
A DISINTEGRIN AND A METALLOPROTEINASE (ADAM)
GPCR
FLUORESCENT ACTIVATED CELL SORTING (FACS)
CELL SURFACE SHEDDING
SMALL INTERFERING RNA (SIRNA)
EGFR SIGNAL TRANSACTIVATION

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