Vaginal pH and microflora related to yeast infections and treatment.

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Abstract
The relationship between vaginal pH, microflora and yeast infection was investigated in 93 women randomly treated with nystatin or miconazole pessaries and cream for 2 wk. Vaginal pH was measured in a control group of 48 women. In the study group 37 patients defaulted, 39 were cured and 17 required treatment during the 6-mo. follow-up period. In study and control groups before and after treatment the mean vaginal pH was 4.3-4.6. Lactobacilli were plentiful in 78 (91%) of 86 patients. Lactobacilli and yeasts commonly co-exist. The influence of other organisms appeared negligible. Nystatin and miconazole were equally effective in the treatment of vaginal yeast infection. The broad-spectrum activity of miconazole offered no advantage in this condition.

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