GRADENIGO'S SYNDROME: ANATOMIC ASPECTS
- 1 January 1931
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 13 (1) , 87-93
- https://doi.org/10.1001/archotol.1931.03660010097011
Abstract
The variations in the distribution of the pneumatic cavities into the remotest parts of the mastoid and petrous portion of the temporal bone were well known for many years. Bezold,1 Politzer,2 Siebenmann, Hyrtl3 and more recently Cheatle4 and Mouret5 accurately described the cellular structure showing the connection with the tympanum. It remained for Gradenigo,6 however, to describe the apical cells systematically and to associate them with the peculiar symptoms that occur infrequently during the course of an acute suppurative otitis media. These signs and symptoms are: (a) abducens paresis or paralysis, (b) severe pain in one or more areas in the distribution of the trigeminal nerve, but most commonly localized in the temporoparietal region, in the eye or deep in the orbit and (c) an acute suppurative otitis media with or without perforation of the membrana tympani. Existing together, these symptoms constitute the "GradenigoKeywords
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