Effect of dopamine-beta-hydroxylase inhibition on cerebral vasospasm in the cat
- 1 February 1976
- journal article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 44 (2) , 168-172
- https://doi.org/10.3171/jns.1976.44.2.0168
Abstract
Inhibitors of dopamine beta hydroxylase (DBH) administered intraperitoneally were shown to prevent spasm of the basilar artery caused by blood application in cats. A low or nondetectable blood DBH activity level may be related to the absence of spasm. In several instances, however, moderate spasm did occur with a low blood DBH activity level. Possible mechanisms for these findings are discussed.Keywords
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