Site-Selective Iodine−Magnesium Exchange Reaction of 1,4-Diiodo-1,3-Alkadienes by an Organomagnesium Ate Complex, and Its Application to Synthesis of Polysubstituted Styrenes and Phenols
- 16 May 2003
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 125 (23) , 6884-6885
- https://doi.org/10.1021/ja0353513
Abstract
When 1,4-diiodo-1,3-alkadienes were treated with i-PrBu2MgLi, highly site-selective iodine−magnesium exchange reaction took place to afford, after the reaction with electrophiles, a variety of 1-iodo-1,3-alkadiene derivatives. Synthetic utility of the reaction was demonstrated by an efficient preparation of polysubstituted styrenes and phenols.Keywords
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