Melanotic neuroectodermal tumor of infancy.Its histological similarities to fetal pineal gland
- 1 April 1977
- Vol. 39 (4) , 1535-1541
- https://doi.org/10.1002/1097-0142(197704)39:4<1535::aid-cncr2820390426>3.0.co;2-0
Abstract
Striking similarities between the pineals of 107 fetuses and infants and a pigmented neuroectodermal tumor occurring in the right orbital and right frontal regions in a 6-month-old Puerto Rican boy were found. Both the human fetal pineal and melanotic neuroectodermal tumors of infancy are characterized by pigmented (melanin) epithelial cells, small undifferentiated cells, and a fibrovascular stroma. Our findings suggest the fetal pineal may be a normally occurring precursor of the melanotic neuroectodermal tumor of infancy, or that melanin production may be a normal capability of differentiating neuroepithelial cells.This publication has 8 references indexed in Scilit:
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