Pyruvate oxidation in pigeon brain catalyzed by fumarate
- 1 January 1946
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 40 (2) , 278-283
- https://doi.org/10.1042/bj0400278
Abstract
Fumarate stimulated O2 uptake of dialyzed pigeon brain suspensions respiring in pyruvate, only when PO4- and adenine nucleotide were also present. The O2/pyruvate ratio approached 2.50, the pyruvate being oxidized completely to CO2 and water. The rate of disappearance of pyruvate was slightly decreased due to oxidation of fumarate to pyruvate, and not due to any effect on rate of utilization of pyruvate but on some intermediary product arising during pyruvate oxidation.Keywords
This publication has 7 references indexed in Scilit:
- Fumaric acid oxidation by ground preparations of pigeon brainBiochemical Journal, 1945
- The in vitro oxidation of pyruvic and α-ketobutyric acids by ground preparations of pigeon brain. The effect of inorganic phosphate and adenine nucleotideBiochemical Journal, 1943
- A general method for the estimation of α-keto-acids, and its application to α-keto-acid metabolism in pigeon brainBiochemical Journal, 1942
- The oxidation of pyruvate by heart muscleBiochemical Journal, 1940
- The oxidation of pyruvate in pigeon breast muscleBiochemical Journal, 1940
- Pyruvate oxidation in brainBiochemical Journal, 1939
- The effect of fumarate on respirationProceedings of the Royal Society of London. B. Biological Sciences, 1936