HEART RATE AND ARTERIAL BLOOD PRESSURE DURING DIFFERENT FORMS OF INDUCTION OF ANAESTHESIA IN PATIENTS WITH MITRAL STENOSIS AND CONSTRICTIVE PERICARDITIS

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Abstract
Twenty-four patients about to undergo surgery for mitral stenosis or constxictive pericarditis were studied by recording intra-arterial blood pressure and heart rate continuously during the induction period. In two groups of patients, narcosis was induced with thiopentone or hexobarbitone. In the third group, induction took place with nitrous oxide. The investigation shows that: (1) A significant increase in blood pressure occurred during intubation in all three groups, and was most marked in the thiopentone group. The blood pressure returned to the initial values in the thiopentone and nitrous oxide groups. Pronounced hypotension appeared in the hexobarbitone group. (2) A significant increase in heart rate during intubation occurred only in the barbiturate groups. Bradycardia appeared in the hexobarbitone group.

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