THE EFFECT OF CORTISONE ON THE URINARY EXCRETION OF 17-KETOSTEROIDS IN PATIENTS WITH CUSHING'S SYNDROME 1

Abstract
The urinary excretion of 17-ketosteroids in 6 patients with Cushing''s syndrome has been studied during a 4- to 5-day period of exogenous cortisone admn. No alteration was observed in the abnormally high excretion of 17-ketosteroids in 1 patient with a metastatic adrenal tumor. Significant decreases in 17-ketosteroid levels were noted in 5 patients with proven hyperplastic adrenal cortices.