SURVIVAL AMONG PATIENTS WITH LIVER METASTASES FROM CANCER OF COLON AND RECTUM

  • 1 January 1976
    • journal article
    • research article
    • Vol. 11, 111-115
Abstract
Factors influencing spontaneous survival in 49 patients with liver metastases after cancer in colon/rectum were evaluated. In addition the same evaluation was performed in 12 patients treated with 5-fluorouracil systemically or intrarterially in the hepatic artery. Alkaline phosphatases, elevated more than 4 times normal values, elevated serum alanine aminotransferase, or jaundice were all unfavorable prognostic signs in the spontaneous group. In the 5-fluorouracil treated group, only elevated serum bilirubin had the same unfavorable prognostic sign. Even though it seems to be an increased survival time in the 5-fluorouracil treated group, metastases to the liver from cancer in colon/rectum seemed more or less resistant to 5-fluorouracil.

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