An improved synthetic route to huperzine A; new analogues and their inhibition of acetylcholinesterase

1 January 1993

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 10,p. 860-862
https://doi.org/10.1039/c39930000860

Abstract

A bicycloannulation approach to huperzine A is detailed together with syntheses of the methylene analogue 8, the diamino compound 12 and their inhibition of acetylcholinesterase.

Keywords

IMPROVED SYNTHETIC
SYNTHETIC ROUTE
HUPERZINE
DIAMINO COMPOUND
METHYLENE ANALOGUE
BICYCLOANNULATION APPROACH
NEW ANALOGUES

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