Malignant Peritoneal Cytology as Prognostic Indicator in Stage I Endometrial Cancer

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Abstract
The prognostic significance of malignant peritoneal cytology was evaluated in 93 patients with stage I endometrial cancer seen at Roswell Park Memorial Institute [New York City,USA]. Eighty-three patients (89%) had negative cytologic samples and 10 (11%) had positive cytology for neoplastic cells. All patients were followed for a minimum of 10 yr or until dead from cancer or intercurrent disease. No patient received treatment for positive cytology. There was 1 recurrence in the patients with positive cytology (10%), and 6 recurrences in the negative group (7%). The actuarial survival rate at 5 and 10 yr for patients with negative cytology was 93.9 and 92.5%, respectively. For patients with positive cytology, the survival was 87.5% at both time intervals. No significant difference was found between the groups. Malignant peritoneal cytology does not seem to be a prognostic indicator in stage I endometrial cancer.