The preparation of dimedone derivatives of amino acids and their use in peptide synthesis
- 1 January 1965
- journal article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 18 (3) , 417-421
- https://doi.org/10.1071/ch9650417
Abstract
The preparation of dimedone derivatives of amino acids has been effected by saponification of the corresponding alkyl esters, and also by catalytic hydrogenation of the respective benzyl esters. The amino acid derivatives have been used to synthesize peptides in excellent yields, employing dicyclohexyl carbodiimide as the condensing agent.Keywords
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