Abstract
The synthesis of novel cardenolides, closely related to naturally-occurring cardiotonic agents, is described. They were obtained from 17β-[3-furyl]androstanes derived from digitoxigenin, gitoxigenin, digoxigenin, and strophanthidin by hypohalous acid or organic peracid oxidation. The preparation of β-D- and α-L-glycosidic derivatives is also reported.

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