Genomic privacy and limits of individual detection in a pool
- 23 August 2009
- journal article
- Published by Springer Nature in Nature Genetics
- Vol. 41 (9) , 965-967
- https://doi.org/10.1038/ng.436
Abstract
Recent studies have demonstrated that statistical methods can be used to detect the presence of a single individual within a study group based on summary data reported from genome-wide association studies (GWAS). We present an analytical and empirical study of the statistical power of such methods. We thereby aim to provide quantitative guidelines for researchers wishing to make a limited number of SNPs available publicly without compromising subjects' privacy.Keywords
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