CHRONIC CHAGAS-DISEASE - UNIMPAIRED DELAYED-TYPE HYPERSENSITIVITY REACTIONS IN CONTRAST WITH HUMORAL SUPPRESSION TO TYPHOID VACCINE

  • 1 January 1981
    • journal article
    • research article
    • Vol. 32  (2) , 82-86
Abstract
Peripheral T and B cells were decreased in patients chronically infected with Trypanosoma cruzi. The humoral response to typhoid vaccine was suppressed in contrast with normal cutaneous delayed type hypersensitivity (DTH) reactions to Candida antigen, PPD [purified protein derivative], SK-SD [streptokinase-streptodornase], Vaccinia virus antigen and DNCB [dinitrochlorobenzene]. Complement and Ig levels were between normal range and no immune complexes were detected by precipitation with polyethylene glycol.