Unchanged sensitivity to noradrenaline in isolated tissues from cold-acclimated rats
- 1 September 1970
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 48 (9) , 657-660
- https://doi.org/10.1139/y70-096
Abstract
Acclimation of rats to cold did not alter either the sensitivity to noradrenaline or the size of the maximum response to noradrenaline of three isolated tissue preparations (chronotropic response of isolated atria; inotropic response of left atrium; contractile response of vas deferens). It is concluded that a change in the response of the heart to exogenous noradrenaline is an unlikely explanation for the modified cardiovascular responses to noradrenaline known to occur in intact cold-acclimated rats.Keywords
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