Transgenic knockouts reveal a critical requirement for pancreatic β cell glucokinase in maintaining glucose homeostasis
- 1 October 1995
- Vol. 83 (1) , 69-78
- https://doi.org/10.1016/0092-8674(95)90235-x
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Liver Glucokinase: Decreased Activity in Patients with Type II DiabetesHormone and Metabolic Research, 1995
- Regulatory effects of glucose on the catalytic activity and cellular content of glucokinase in the pancreatic beta cell. Study using cultured rat islets.Journal of Clinical Investigation, 1994
- In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents.Journal of Clinical Investigation, 1994
- Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations.Journal of Clinical Investigation, 1994
- Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes.Journal of Clinical Investigation, 1993
- Deletion of the donor splice site of intron 4 in the glucokinase gene causes maturity-onset diabetes of the young.Journal of Clinical Investigation, 1993
- Nonsense mutation of glucokinase gene in late-onset non-insulin-dependent diabetes mellitusThe Lancet, 1992
- Linkage of type 2 diabetes to the glucokinase geneThe Lancet, 1992
- Hexokinase and ‘glucokinase’ in liver metabolismTrends in Biochemical Sciences, 1991
- Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gammaCell, 1988