Hepatitis A: Detection by Immune Electron Microscopy of a Viruslike Antigen Associated with Acute Illness
- 7 December 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 182 (4116) , 1026-1028
- https://doi.org/10.1126/science.182.4116.1026
Abstract
Spherical 27-nanometer particles were visualized in stools obtained from hepatitis A patients in the acute phase of the disease. The particle was serologically specific for this disease, and every hepatitis A patient tested demonstrated a serologic response to this antigen. The findings suggest that it is the etiologic agent of hepatitis A.Keywords
This publication has 17 references indexed in Scilit:
- Etiologic Relationship of Marmoset-Propagated CR326 Hepatitis A Virus to Hepatitis in ManExperimental Biology and Medicine, 1973
- Density in Cesium Chloride of the 27 nm "8FIIa" Particle Associated with Acute Infectious Nonbacterial Gastroenteritis: Determination by Ultra-centrifugation and Immune Electron MicroscopyExperimental Biology and Medicine, 1973
- Identification of the Kirk "Hepatitis" Virus as a Member of the Parvovirus (Picodnavirus) GroupExperimental Biology and Medicine, 1971
- Properties of a Virus Isolated from Patients with MS-1 Infectious HepatitisThe Journal of Infectious Diseases, 1971
- VIRUS‐LIKE PARTICLES ASSOCIATED WITH A FAECAL ANTIGEN FROM HEPATITIS PATIENTS AND WITH AUSTRALIA ANTIGENImmunology & Cell Biology, 1971
- Preparation and Characterization of Complement-fixing Hepatitis-associated Antigen and AntiserumThe Journal of Infectious Diseases, 1970
- The Morphology of Virus-Antibody InteractionPublished by Elsevier ,1969
- A Serum Antigen (Australia Antigen) in Down's Syndrome, Leukemia, and HepatitisAnnals of Internal Medicine, 1967
- A "New" Antigen in Leukemia SeraJAMA, 1965
- The natural history of infectious hepatitisThe American Journal of Medicine, 1962