Sex-Related Difference in Antral and Serum Gastrin Levels in the Rat
- 1 April 1976
- journal article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 151 (4) , 785-788
- https://doi.org/10.3181/00379727-151-39307
Abstract
Antral and serum gastrin concentrations were found to be significantly lower in female than in male rats. Following ovariectomy, serum gastrin concentration significantly increased to male levels; tissue gastrin also increased, but not significantly. Daily injections of estradiol benzoate (2 mug/day) abolished the rise in gastrin levels after ovariectomy. Antral and serum gastrin concentrations were significantly higher in lactating rats than in any other group tested. The possible relationships among sex-dependent changes in food intake, gastrin concentration, and gastric secretion are discussed.Keywords
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