Folate sensitive site at 10q23 and its expression as a deletion.
- 1 May 1987
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 24 (5) , 299
- https://doi.org/10.1136/jmg.24.5.299
Abstract
A patient is reported for whom initial chromosome anlaysis indicated 45,X/46,XX/46,XX,10q- mosaicism. The clinical findings included hypothyroidism and a low red cell folate estimation. The deleted chromosome 10 was subsequently shown to be an extreme expression of the folate sensitive heritable fragile site at 10q23, and a possible association between this and the in vivo folate status of the patient is suggested.This publication has 4 references indexed in Scilit:
- Deleted X chromosomes in patients with the fragile X syndrome.Journal of Medical Genetics, 1984
- The Lymphocyte as a Marker of Past Nutritional Status: Persistence of Abnormal Lymphocyte Deoxyuridine (dU) Suppression Test and Chromosomes in Patients with Past Deficiency of Folate and Vitamin B12*British Journal of Haematology, 1978
- Megaloblastic Anemia Secondary to Folate Deficiency Associated with HypothyroidismAnnals of Internal Medicine, 1968