CHEMICAL SURVEILLANCE AND QUALITY ASSURANCE FOR PREPARATION OF DOSED (2-AAF) ANIMAL FEED (ED01 STUDY)

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 3, 203-210
Abstract
Protocol development of the ED01 [effective dose producing a 1% tumor rate] experiment included assurances that only minimal levels of contaminants were present and correct concentrations of 2-AAF [2-acetylaminofluorene] were present in animal feed. Laboratory and administrative controls were developed to assure proper feed packaging and delivery, and to conduct both personnel and chemical surveillance of work environs to ensure safe work areas. Animal feed and ancillary animal supplies were monitored prior to use to provide assurances that acceptable levels of nutrients were present and to prohibit the entrance of unacceptable levels of contaminants such as pesticides and heavy metals.

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