Infectious Agents in Infant Diarrhea: II. Serological Reactions with Escherichia coli 01 through 025

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Abstract
While Escherichia coli serotypes 01 through 025 have been described as possessing pathogenic properties, no attempt to relate these organisms to infant diarrhea has met with success. In the present study it was revealed that almost half of the infants carrying Escherichia coli 01 through 025 in their intestinal tract during a diarrheal attack exhibited a rise in hemagglutinin titer. A greater number had inhibitors present in their sera which were antigenically related to the E. coli serotype isolated from their fecal flora. These findings do not afford proof of contribution to the disease state, but can be interpreted as evidence of a dynamic relationship existing between infant host and the E. coli present in the intestine.

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