RESTITUTION OF STREPTOZOTOCIN INDUCED DIABETES MELLITUS IN NUDE MICE WITH PANCREATIC GRAFTS FROM THE RAT
- 1 November 1976
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section C Immunology
- Vol. 84C (3) , 221-226
- https://doi.org/10.1111/j.1699-0463.1976.tb00023.x
Abstract
Transplants of 1‐3 rat pancreases have proven to restitute streptozotocin induced diabetes in athymic nude mice. One out of 9 diabetic nude mice showed restitution following subcutaneous implantation of 1 rat pancreas. Three out of 6 nude mice were restituted by 2‐3 grafts. Implants of rat submandibular gland did not restitute nude mice similarly treated with streptozotocin. The model seems of interest in studies of inter‐species transplantation of pancreas.Keywords
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