Linear energy transfer (LET) effects in the radiation-induced inactivation of papain
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Faraday Discussions of the Chemical Society
- Vol. 63, 237-247
- https://doi.org/10.1039/dc9776300237
Abstract
The inactivation of dilute aqueous solutions of papain by radiations of varying linear energy transfer has been studied in N2, N2O and O2-saturated solutions. The results obtained with low LET radiation are very similar to those previously reported by Lin, Clement, Gaucher and Armstrong. The additional data obtained at higher LET, when radical product yields are reduced and the yield of hydrogen peroxide is increased, show that the hydrogen atom is more important in the inactivation of papain than previously considered.Keywords
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