Helioferins; Novel Antifungal Lipopeptides From Mycogone rosea: Screening, Isolation, Structures and Biological Properties.
- 1 January 1995
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 48 (2) , 126-133
- https://doi.org/10.7164/antibiotics.48.126
Abstract
Helioferins A and B were detected as novel aminolipopeptides in cultures of Mycogone rosea DSM 8822 in the course of a screening for mediators of helianthate anion transfer from aqueous to toluene phases. Their structures as novel antibiotics and cytotoxic agents were elucidated by mass spectrometry and NMR spectroscopic methods. Antimicrobial activity was estimated against Candida albicans and Gram-positive bacteria including Mycobacterium spp.Keywords
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