MECHANISM OF SPREAD OF ASIAN INFLUENZA

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Abstract
Asian influenza spread widely in a susceptible population. The most susceptible group proved to be the 5- to 19-year-olds. The high attack rate resulted from a number of variables: nonspecific susceptibility, lack of protective antibodies, and contact in schools. The school appeared to be a more important site of virus dissemination than did the home. The long intervals between 1st and 2d, cases in families, and the longer interval between 1st introductions of virus and epidemics in nations suggest that the possible seeding of "masked" virus prior to the appearance of clinical disease should be investigated the next time we have an opportunity to anticipate an epidemic.

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