Changes in Plasma Proteins of Mice During Rejection of Skin Homografts and Heterografts.

Abstract
Following application of a single homograft or heterograft of full thickness skin, albumin, alpha 1, beta, and gamma globulin fractions of the plasma proteins of C3H mice remain unchanged as compared to changes following autografting while the alpha 2 fraction increases significantly. Repeated grafting resulted in higher alpha 2 levels than did a single graft A return to normal of the alpha 2 fraction could be produced by excising the homograft or heterograft before necrosis occurred.

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